Does The Use Of Salvia Divinorum Prolong The Blood Clotting Time?

Interaction Between Warfarin and Danshen (sage miltiorrhizaBy Chan TYK in Annals of Pharmacotherapy Vol .35 , pp . 501-504This close is an attempt to substantiate the traditional hold of the salvia miltiorrhiza flora , comm unless known as dan shen , in eliminating riptide stasis and enhancing phase circulation as indicated by Traditional Chinese Medicine . The Chinese go for long utilise it to accelerate menstrual business flow and is withal prescribed to patients with cardiovascular diseases as easily as other ailmentsConducted in 2001 , Chan s work focused on the interaction of these two substances in human being . He inspectioned the cases of terzetto patients who were taking long term warfarin treatments and then took Salvia miltiorrhiza (commonly known as dan shen ) after some time . They buzz offed from anti coagulant medication medication overdose with excessive bleeding that led to complications . Dan shen was receive as the cause of the overdose in the said cases because thither were no other components to which it could be attrisolelyed toAs scientific evidence on dan shen s rear on blood clotting time is insufficient , this theatre adds to the current knowledge on this aspect It alike points to the potentials of the herb for the development of an alternative anti-coagulant especi ally for patients suffering from blastoff and the accompanying blood clotting in the brain . currently , ceremonious Western medicines hasten so far proven sufficient for effective treatmentsThere atomic number 18 limitations in the study . Because it only reviewed tether cases of warfarin and dan shen use with bleeding complications , the sample would not search to be representative of all the cases involving the use of both(prenominal) substances . come on , the researcher failed to ascer tain the dosages of dan shen taken by the pa! tients as hale as the severity of overdose establish on the dosages ingested that would dish magnify the passs of the studyAlso , subjecting the dan shen substances to chemical analysis so as to discriminate its various components and identify which slows down factor II bodily process would endure been beneficial to the study . It whitethorn also be viable that the warfarin medication used did not meet the set up standard for the establish of the drug for it to cause adverse array effects but in assuming that it did meet standards , warfarin was eliminated as a factor in itselfThe prolonged use of the medicine , as was the case in the patients could also have predisposed them to suffer from excessive bleeding . The differences in the lengths of warfarin treatment should also have been considered as a factor .

However , it does maintenance physicians against allowing patients to take both warfarin and on the fence(p) amounts of dan shenWhen seen in semblance to the overall effort of establishing the anticoagulant performance of dan shen in humans , this study would only establish the fortune for such properties because it is presumed to have caused the said overdose . However , it does not conclusively determine that the intake of the herb does result in such activity in humans such that when unite with drugs with the aforesaid(prenominal) properties , it would result in anti-coagulant overdoseMore compelling evidence croup be complete(a) for both the interaction of warfarin and dan shen if a double-blind study were to be conducted involving randomly selected participants divided into control and placebo groups . geminate blind studies are also nece ssary to conclude on its anti-coagulant property and ! in to be reliableBecause dan shen has been traditionally established as an anticoagulant , a non-double-blind study would result in many a(prenominal) possible biases that overcloud the conclusions . It should also be replicated to determine if all studies reach the same conclusions . In vitro studies involving dan shen treatment or the crew of dan shen and warfarin are also essentialList of ReferencesOliff , H .S (2001 . Chinese herb Danshen Interacts with Warfarin causation Longer Bleeding Time . Retreived 4 April 2008 from http /www .physiologics .com /herbclip /review .asp ?i 42690 PAGEPAGE 3 ...If you involve to get a unspoiled essay, order it on our website: OrderEssay.net

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